As the year comes to an end, I am off to my final business trip of the year in Washington, D.C. As such, I will be taking a little break from blogging from December 13 to January 3. Posts will resume in the New Year.
I would like to wish the loyal readers of P2C2E a Happy Holidays.
Like any new process, it takes some practice to extract, understand and convert the information presented from a set of experimental NMR datasets into a fragment.
The only fragment that can accommodate the set of restrictions from a 1H-13C HSQC and HMBC is 2,3-dimethylbutane-1,1-diyl. The green arrows illustrate the 2-3JCH coupling responses extracted from an HMBC experiment.
